What do Cochrane systematic reviews say about interventions for insomnia?
Identifieur interne : 000666 ( Main/Exploration ); précédent : 000665; suivant : 000667What do Cochrane systematic reviews say about interventions for insomnia?
Auteurs : Florence De Lucca Melo [Brésil] ; Juan Fulgencio Welko Mendoza [Brésil] ; Carolina De Oliveira Cruz Latorraca [Brésil] ; Rafael Leite Pacheco [Brésil] ; Ana Luiza Cabrera Martimbianco [Brésil] ; Daniela Vianna Pachito [Brésil] ; Rachel Riera [Brésil]Source :
- Sao Paulo medical journal = Revista paulista de medicina [ 1806-9460 ]
Descripteurs français
- KwdFr :
- Antidépresseurs (usage thérapeutique), Essais contrôlés randomisés comme sujet (MeSH), Exercice physique (MeSH), Humains (MeSH), Musicothérapie (normes), Médecine factuelle (MeSH), Revues systématiques comme sujet (MeSH), Sommeil (physiologie), Thérapie par acupuncture (normes), Troubles de l'endormissement et du maintien du sommeil (thérapie), Troubles de l'endormissement et du maintien du sommeil (traitement médicamenteux).
- MESH :
- normes : Musicothérapie, Thérapie par acupuncture.
- physiologie : Sommeil.
- thérapie : Troubles de l'endormissement et du maintien du sommeil.
- traitement médicamenteux : Troubles de l'endormissement et du maintien du sommeil.
- usage thérapeutique : Antidépresseurs.
- Essais contrôlés randomisés comme sujet, Exercice physique, Humains, Médecine factuelle, Revues systématiques comme sujet.
English descriptors
- KwdEn :
- Acupuncture Therapy (standards), Antidepressive Agents (therapeutic use), Evidence-Based Medicine (MeSH), Exercise (MeSH), Humans (MeSH), Music Therapy (standards), Randomized Controlled Trials as Topic (MeSH), Sleep (physiology), Sleep Initiation and Maintenance Disorders (drug therapy), Sleep Initiation and Maintenance Disorders (therapy), Systematic Reviews as Topic (MeSH).
- MESH :
- chemical , therapeutic use : Antidepressive Agents.
- drug therapy : Sleep Initiation and Maintenance Disorders.
- physiology : Sleep.
- standards : Acupuncture Therapy, Music Therapy.
- therapy : Sleep Initiation and Maintenance Disorders.
- Evidence-Based Medicine, Exercise, Humans, Randomized Controlled Trials as Topic, Systematic Reviews as Topic.
Abstract
CONTEXT AND OBJECTIVE
Insomnia is a frequent complaint that generates more than five million visits to doctors per year in the United States. This study summarizes all Cochrane systematic reviews (SRs) that evaluated interventions to treat insomnia.
DESIGN AND SETTING
Review of SRs, conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP).
METHODS
A sensitive search was carried out in the Cochrane Database of Systematic Reviews to identify Cochrane SRs that assessed the effects of any type of intervention for people with insomnia. The results, main characteristics of the SRs and the certainty of the evidence obtained from them were synthesized and discussed.
RESULTS
Seven SRs were included. They addressed the benefits and harm of acupuncture (n = 1), behavioral interventions (n = 1), music (n = 1), pharmacotherapy (n = 2), phototherapy (n = 1) and physical exercise (n = 1). The certainty of the evidence ranged from moderate to very low.
CONCLUSION
Acupuncture, music, physical exercise, paroxetine, doxepin, trimipramine and trazodone seem to present some benefit for patients with insomnia. However, the uncertainty around these results means that no robust and definitive recommendations for clinical practice can be made until the benefits and harms from each intervention for patients with insomnia have been confirmed through further studies.
DOI: 10.1590/1516-3180.2018.0380311018
PubMed: 30892489
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Rheumatologist; Adjunct Professor, Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP); and Researcher, Cochrane Brazil, São Paulo (SP)</wicri:regionArea><wicri:noRegion>São Paulo (SP)</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2018">2018 Nov-Dec</date><idno type="RBID">pubmed:30892489</idno><idno type="pmid">30892489</idno><idno type="doi">10.1590/1516-3180.2018.0380311018</idno><idno type="wicri:Area/Main/Corpus">000565</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000565</idno><idno type="wicri:Area/Main/Curation">000565</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000565</idno><idno type="wicri:Area/Main/Exploration">000565</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">What do Cochrane systematic reviews say about interventions for insomnia?</title><author><name sortKey="Melo, Florence De Lucca" sort="Melo, Florence De Lucca" uniqKey="Melo F" first="Florence De Lucca" last="Melo">Florence De Lucca Melo</name><affiliation wicri:level="1"><nlm:affiliation>Undergraduate Medical Student, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Undergraduate Medical Student, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo (SP)</wicri:regionArea><wicri:noRegion>São Paulo (SP)</wicri:noRegion></affiliation></author><author><name sortKey="Mendoza, Juan Fulgencio Welko" sort="Mendoza, Juan Fulgencio Welko" uniqKey="Mendoza J" first="Juan Fulgencio Welko" last="Mendoza">Juan Fulgencio Welko Mendoza</name><affiliation wicri:level="1"><nlm:affiliation>Undergraduate Medical Student, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Undergraduate Medical Student, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo (SP)</wicri:regionArea><wicri:noRegion>São Paulo (SP)</wicri:noRegion></affiliation></author><author><name sortKey="Latorraca, Carolina De Oliveira Cruz" sort="Latorraca, Carolina De Oliveira Cruz" uniqKey="Latorraca C" first="Carolina De Oliveira Cruz" last="Latorraca">Carolina De Oliveira Cruz Latorraca</name><affiliation wicri:level="1"><nlm:affiliation>MSc. Psychologist; Postgraduate Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP); and Assistant Researcher, Cochrane Brazil, São Paulo (SP), Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>MSc. Psychologist; Postgraduate Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP); and Assistant Researcher, Cochrane Brazil, São Paulo (SP)</wicri:regionArea><wicri:noRegion>São Paulo (SP)</wicri:noRegion></affiliation></author><author><name sortKey="Pacheco, Rafael Leite" sort="Pacheco, Rafael Leite" uniqKey="Pacheco R" first="Rafael Leite" last="Pacheco">Rafael Leite Pacheco</name><affiliation wicri:level="1"><nlm:affiliation>MD. Postgraduate Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP), and Assistant Researcher, Cochrane Brazil, São Paulo (SP), Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>MD. Postgraduate Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP), and Assistant Researcher, Cochrane Brazil, São Paulo (SP)</wicri:regionArea><wicri:noRegion>São Paulo (SP)</wicri:noRegion></affiliation></author><author><name sortKey="Martimbianco, Ana Luiza Cabrera" sort="Martimbianco, Ana Luiza Cabrera" uniqKey="Martimbianco A" first="Ana Luiza Cabrera" last="Martimbianco">Ana Luiza Cabrera Martimbianco</name><affiliation wicri:level="1"><nlm:affiliation>MSc, PhD. Physiotherapist; Postdoctoral Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP); Professor, Health and Environment Program, Universidade Metropolitana de Santos (UNIMES); and Volunteer Researcher, Cochrane Brazil, São Paulo (SP), Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>MSc, PhD. Physiotherapist; Postdoctoral Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP); Professor, Health and Environment Program, Universidade Metropolitana de Santos (UNIMES); and Volunteer Researcher, Cochrane Brazil, São Paulo (SP)</wicri:regionArea><wicri:noRegion>São Paulo (SP)</wicri:noRegion></affiliation></author><author><name sortKey="Pachito, Daniela Vianna" sort="Pachito, Daniela Vianna" uniqKey="Pachito D" first="Daniela Vianna" last="Pachito">Daniela Vianna Pachito</name><affiliation wicri:level="1"><nlm:affiliation>MD, MSc. Neurologist; Postgraduate Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP); and Assistant Researcher, Cochrane Brazil, São Paulo (SP), Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>MD, MSc. Neurologist; Postgraduate Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP); and Assistant Researcher, Cochrane Brazil, São Paulo (SP)</wicri:regionArea><wicri:noRegion>São Paulo (SP)</wicri:noRegion></affiliation></author><author><name sortKey="Riera, Rachel" sort="Riera, Rachel" uniqKey="Riera R" first="Rachel" last="Riera">Rachel Riera</name><affiliation wicri:level="1"><nlm:affiliation>MD, MSc, PhD. Rheumatologist; Adjunct Professor, Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP); and Researcher, Cochrane Brazil, São Paulo (SP), Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>MD, MSc, PhD. Rheumatologist; Adjunct Professor, Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP); and Researcher, Cochrane Brazil, São Paulo (SP)</wicri:regionArea><wicri:noRegion>São Paulo (SP)</wicri:noRegion></affiliation></author></analytic><series><title level="j">Sao Paulo medical journal = Revista paulista de medicina</title><idno type="eISSN">1806-9460</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acupuncture Therapy (standards)</term><term>Antidepressive Agents (therapeutic use)</term><term>Evidence-Based Medicine (MeSH)</term><term>Exercise (MeSH)</term><term>Humans (MeSH)</term><term>Music Therapy (standards)</term><term>Randomized Controlled Trials as Topic (MeSH)</term><term>Sleep (physiology)</term><term>Sleep Initiation and Maintenance Disorders (drug therapy)</term><term>Sleep Initiation and Maintenance Disorders (therapy)</term><term>Systematic Reviews as Topic (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Antidépresseurs (usage thérapeutique)</term><term>Essais contrôlés randomisés comme sujet (MeSH)</term><term>Exercice physique (MeSH)</term><term>Humains (MeSH)</term><term>Musicothérapie (normes)</term><term>Médecine factuelle (MeSH)</term><term>Revues systématiques comme sujet (MeSH)</term><term>Sommeil (physiologie)</term><term>Thérapie par acupuncture (normes)</term><term>Troubles de l'endormissement et du maintien du sommeil (thérapie)</term><term>Troubles de l'endormissement et du maintien du sommeil (traitement médicamenteux)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antidepressive Agents</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Sleep Initiation and Maintenance Disorders</term></keywords><keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Musicothérapie</term><term>Thérapie par acupuncture</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Sommeil</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Sleep</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Acupuncture Therapy</term><term>Music Therapy</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Sleep Initiation and Maintenance Disorders</term></keywords><keywords scheme="MESH" qualifier="thérapie" xml:lang="fr"><term>Troubles de l'endormissement et du maintien du sommeil</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Troubles de l'endormissement et du maintien du sommeil</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antidépresseurs</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Evidence-Based Medicine</term><term>Exercise</term><term>Humans</term><term>Randomized Controlled Trials as Topic</term><term>Systematic Reviews as Topic</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Essais contrôlés randomisés comme sujet</term><term>Exercice physique</term><term>Humains</term><term>Médecine factuelle</term><term>Revues systématiques comme sujet</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>CONTEXT AND OBJECTIVE</b></p><p>Insomnia is a frequent complaint that generates more than five million visits to doctors per year in the United States. This study summarizes all Cochrane systematic reviews (SRs) that evaluated interventions to treat insomnia.</p></div><div type="abstract" xml:lang="en"><p><b>DESIGN AND SETTING</b></p><p>Review of SRs, conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP).</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>A sensitive search was carried out in the Cochrane Database of Systematic Reviews to identify Cochrane SRs that assessed the effects of any type of intervention for people with insomnia. The results, main characteristics of the SRs and the certainty of the evidence obtained from them were synthesized and discussed.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Seven SRs were included. They addressed the benefits and harm of acupuncture (n = 1), behavioral interventions (n = 1), music (n = 1), pharmacotherapy (n = 2), phototherapy (n = 1) and physical exercise (n = 1). The certainty of the evidence ranged from moderate to very low.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Acupuncture, music, physical exercise, paroxetine, doxepin, trimipramine and trazodone seem to present some benefit for patients with insomnia. However, the uncertainty around these results means that no robust and definitive recommendations for clinical practice can be made until the benefits and harms from each intervention for patients with insomnia have been confirmed through further studies.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30892489</PMID><DateCompleted><Year>2019</Year><Month>06</Month><Day>05</Day></DateCompleted><DateRevised><Year>2019</Year><Month>06</Month><Day>05</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1806-9460</ISSN><JournalIssue CitedMedium="Internet"><Volume>136</Volume><Issue>6</Issue><PubDate><MedlineDate>2018 Nov-Dec</MedlineDate></PubDate></JournalIssue><Title>Sao Paulo medical journal = Revista paulista de medicina</Title><ISOAbbreviation>Sao Paulo Med J</ISOAbbreviation></Journal><ArticleTitle>What do Cochrane systematic reviews say about interventions for insomnia?</ArticleTitle><Pagination><MedlinePgn>579-585</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S1516-31802018000600579</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1590/1516-3180.2018.0380311018</ELocationID><Abstract><AbstractText Label="CONTEXT AND OBJECTIVE" NlmCategory="OBJECTIVE">Insomnia is a frequent complaint that generates more than five million visits to doctors per year in the United States. This study summarizes all Cochrane systematic reviews (SRs) that evaluated interventions to treat insomnia.</AbstractText><AbstractText Label="DESIGN AND SETTING" NlmCategory="METHODS">Review of SRs, conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP).</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A sensitive search was carried out in the Cochrane Database of Systematic Reviews to identify Cochrane SRs that assessed the effects of any type of intervention for people with insomnia. The results, main characteristics of the SRs and the certainty of the evidence obtained from them were synthesized and discussed.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Seven SRs were included. They addressed the benefits and harm of acupuncture (n = 1), behavioral interventions (n = 1), music (n = 1), pharmacotherapy (n = 2), phototherapy (n = 1) and physical exercise (n = 1). The certainty of the evidence ranged from moderate to very low.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Acupuncture, music, physical exercise, paroxetine, doxepin, trimipramine and trazodone seem to present some benefit for patients with insomnia. However, the uncertainty around these results means that no robust and definitive recommendations for clinical practice can be made until the benefits and harms from each intervention for patients with insomnia have been confirmed through further studies.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Melo</LastName><ForeName>Florence de Lucca</ForeName><Initials>FL</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-5688-4533</Identifier><AffiliationInfo><Affiliation>Undergraduate Medical Student, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mendoza</LastName><ForeName>Juan Fulgencio Welko</ForeName><Initials>JFW</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-1616-0231</Identifier><AffiliationInfo><Affiliation>Undergraduate Medical Student, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Latorraca</LastName><ForeName>Carolina de Oliveira Cruz</ForeName><Initials>COC</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-9146-4684</Identifier><AffiliationInfo><Affiliation>MSc. Psychologist; Postgraduate Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP); and Assistant Researcher, Cochrane Brazil, São Paulo (SP), Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pacheco</LastName><ForeName>Rafael Leite</ForeName><Initials>RL</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-7487-8471</Identifier><AffiliationInfo><Affiliation>MD. Postgraduate Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP), and Assistant Researcher, Cochrane Brazil, São Paulo (SP), Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Martimbianco</LastName><ForeName>Ana Luiza Cabrera</ForeName><Initials>ALC</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-4361-4526</Identifier><AffiliationInfo><Affiliation>MSc, PhD. Physiotherapist; Postdoctoral Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP); Professor, Health and Environment Program, Universidade Metropolitana de Santos (UNIMES); and Volunteer Researcher, Cochrane Brazil, São Paulo (SP), Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pachito</LastName><ForeName>Daniela Vianna</ForeName><Initials>DV</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-7052-7735</Identifier><AffiliationInfo><Affiliation>MD, MSc. Neurologist; Postgraduate Student, Evidence-Based Health Program, Universidade Federal de São Paulo (UNIFESP); and Assistant Researcher, Cochrane Brazil, São Paulo (SP), Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Riera</LastName><ForeName>Rachel</ForeName><Initials>R</Initials><Identifier Source="ORCID">http://orcid.org/0000-0002-9522-1871</Identifier><AffiliationInfo><Affiliation>MD, MSc, PhD. Rheumatologist; Adjunct Professor, Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP); and Researcher, Cochrane Brazil, São Paulo (SP), Brazil.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Brazil</Country><MedlineTA>Sao Paulo Med J</MedlineTA><NlmUniqueID>100897261</NlmUniqueID><ISSNLinking>1516-3180</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000928">Antidepressive Agents</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D015670" MajorTopicYN="N">Acupuncture Therapy</DescriptorName><QualifierName UI="Q000592" MajorTopicYN="N">standards</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000928" MajorTopicYN="N">Antidepressive Agents</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019317" MajorTopicYN="Y">Evidence-Based Medicine</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015444" MajorTopicYN="N">Exercise</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009147" MajorTopicYN="N">Music Therapy</DescriptorName><QualifierName UI="Q000592" MajorTopicYN="N">standards</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016032" MajorTopicYN="N">Randomized Controlled Trials as Topic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012890" MajorTopicYN="N">Sleep</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007319" MajorTopicYN="N">Sleep Initiation and Maintenance Disorders</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000078202" MajorTopicYN="Y">Systematic Reviews as Topic</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year><Month>10</Month><Day>10</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2018</Year><Month>10</Month><Day>31</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2019</Year><Month>3</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2019</Year><Month>3</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>6</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">30892489</ArticleId><ArticleId IdType="pii">S1516-31802018000600579</ArticleId><ArticleId IdType="doi">10.1590/1516-3180.2018.0380311018</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Brésil</li></country></list><tree><country name="Brésil"><noRegion><name sortKey="Melo, Florence De Lucca" sort="Melo, Florence De Lucca" uniqKey="Melo F" first="Florence De Lucca" last="Melo">Florence De Lucca Melo</name></noRegion><name sortKey="Latorraca, Carolina De Oliveira Cruz" sort="Latorraca, Carolina De Oliveira Cruz" uniqKey="Latorraca C" first="Carolina De Oliveira Cruz" last="Latorraca">Carolina De Oliveira Cruz Latorraca</name><name sortKey="Martimbianco, Ana Luiza Cabrera" sort="Martimbianco, Ana Luiza Cabrera" uniqKey="Martimbianco A" first="Ana Luiza Cabrera" last="Martimbianco">Ana Luiza Cabrera Martimbianco</name><name sortKey="Mendoza, Juan Fulgencio Welko" sort="Mendoza, Juan Fulgencio Welko" uniqKey="Mendoza J" first="Juan Fulgencio Welko" last="Mendoza">Juan Fulgencio Welko Mendoza</name><name sortKey="Pacheco, Rafael Leite" sort="Pacheco, Rafael Leite" uniqKey="Pacheco R" first="Rafael Leite" last="Pacheco">Rafael Leite Pacheco</name><name sortKey="Pachito, Daniela Vianna" sort="Pachito, Daniela Vianna" uniqKey="Pachito D" first="Daniela Vianna" last="Pachito">Daniela Vianna Pachito</name><name sortKey="Riera, Rachel" sort="Riera, Rachel" uniqKey="Riera R" first="Rachel" last="Riera">Rachel Riera</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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